b'INNOVATIVE RESEARCHERSThe Pediatric Cancer Research Foundation supported these imaginative and far-sighted scientists whose findings set the stage for future advances in care:Susann Brady-Kalnay, PhDTheodore Moore, MD Case Western Reserve University HospitalMattel Childrens Hospital/UCLAUse of magnetic resonance fingerprinting for determining response toPhase I/II therapeutic research trials and development of new treatment immunotherapy in pediatric brain tumorsmodality for incurable brain tumorsMitchell Cairo, MD Marie Nelson, MD New York Medical College, Marie Fareri Childrens HospitalChildrens National Hospital Cancer genetics, tumor immunology and targeted treatments for childhood Neoadjuvant checkpoint inhibition and cryoablation therapy in relapsed or and adolescent hematological malignancies and solid tumorsrefractory pediatric solid tumors Brian Crompton, MDCody Nesvick, MD Dana-Farber Cancer InstituteMayo ClinicProspective validation of a prognostic liquid biopsy approach for pediatric Understand how SMARCB1 loss makes atypical teratoid rhabdoid tumor Ewing sarcoma(AT/RT) cells more vulnerable to treatmentGregory Friedman, MDAshley Plant-Fox, MD University of Alabama at Birmingham and MD Anderson Cancer Center Ann & Robert H. Lurie Childrens Hospital of Chicago Directed drug delivery for pediatric high-grade glioma Combination immunotherapy for diffuse intrinsic pontine glioma (DIPG)Rintaro Hashizume, MD, PhD Kathleen Sakamoto, MD, PhD University of Alabama at Birmingham Lucile Packard Childrens Hospital Stanford Intranasal delivery of targeting nanoliposomal therapeutics for pediatric Exploration of mitochondrial pathway targeting for treatment of pediatric glioma acute myeloid leukemia (AML) Alex Kentsis, MDSurojit Sarkar, PhD Memorial Sloan-Kettering Cancer CenterSeattle Childrens Research Institute Curative epigenetic therapies of refractory pediatric sarcomasDesign of self-driving CAR T cell immunotherapies for metastatic solid tumors Eugenie Kleinerman, MD MD Anderson Cancer CenterElliot Stieglitz, MD A novel dendritic cell vaccine and anti-PD1 for osteosarcoma therapyUniversity of California, San Francisco Benioff Childrens Hospital Innovative tests to determine treatment responsiveness for juvenile Audrey Lasry, MDmyelomonocytic leukemia (JMML) New York University School of Medicine Modulation of the immune microenvironment in pediatric acute myeloidMasataka Suzuki, PhD leukemia (AML)Baylor College of MedicineImmunotherapy and CAR NK cell therapy for pediatric sarcomas John Ligon, MD University of FloridaRajkumar Venkatramani, MD, MS, MBA, FAAPInvestigation of the immune response to RNA-nanoparticle vaccines and Texas Childrens Hospital use of these vaccines in combination with immune checkpoint inhibitors Molecular characterization of undifferentiated sarcomafor metastatic osteosarcomaLeo Wang, MD, PhD Michelle Monje, MD, PhDCity of HopeLucile Packard Childrens Hospital StanfordExploration of the signaling and activation of T cells expanded in Therapies for high-grade glioma immunotherapy9'