Dr. Agnieszka Czechowicz
Emerging Research Grant
– Acute Myeloid Leukemia
Dr. Agnieszka Czechowicz’s Research
Dr. Agnieszka Czechowicz is tackling the most challenging of research barriers in finding new and effective options for children with Acute myeloid leukemia (AML), an unfortunately common and aggressive form of leukemia. Today, treatment of AML involves harsh conventional chemotherapy +/-bone marrow transplantation (BMT); despite this, relapse is high with an overall survival of only ~50%. With her team at Lucille Packard Children’s Hospital, she has pioneered several new antibody therapies targeting KIT, an important membrane-bound receptor (for a key nutrient called SCF) found on bone marrow stem cells and AML cancer cells. They will be testing these antibodies as stand-alone drugs and in combination with BMT in mouse models of pediatric and adult AML. We believe such therapies could rapidly become important curative treatments for AML.
Pediatric Cancer Research Foundation is proud to support the ground breaking research at Stanford University and Lucile Packard Children’s Hospital.